Diagnostic Algorithm for Surgical Management of Limbal Stem Cell Deficiency.

ABSTRACT:

Background

Limbal stem cell deficiency (LCSD) presents several challenges. Currently, there is no clearly defined systematic approach to LSCD diagnosis that may guide surgical tactics.

Methods

The medical records of 34 patients with LSCD were analyzed. Diagnostic modalities included standard (visometry, tonometry, visual field testing, slit-lamp biomicroscopy with corneal fluorescein staining, Schirmer test 1, ultrasonography) and advanced ophthalmic examination methods such as anterior segment optical coherence tomography, in vivo confocal microscopy, impression cytology, and enzyme-linked immunoassay.

Results

Standard ophthalmological examination was sufficient to establish the diagnosis of LSCD in 20 (58.8%) cases, whereas advanced evaluation was needed in 14 (41.2

SUBMITTER: Malyugin B 

PROVIDER: S-EPMC9858342 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature