Genetic and Morphological Variation in Hypodontia of Maxillary Lateral Incisors.

ABSTRACT: (1) Background: Hypodontia has a multifactorial aetiology, in which genetic factors are a major component. Associated with this congenital absence, the formed teeth may show differences in size and shape, which may vary with the specific genetic variants and with the location of the missing teeth. The aims of the present study were to investigate a specific variant of MSX1, derive morphometric tooth measurements in a sample of patients with isolated maxillary lateral incisor agenesis and matched controls, and model the findings. (2) Methods: Genotyping of the MSX1 rs8670 genetic variant and morphometric measurements with a 2D image analysis method were performed for 26 hypodontia patients and 26 matched controls. (3) Results: The risk of upper lateral incisor agenesis was 6.9

SUBMITTER: Kerekes-Mathe B 

PROVIDER: S-EPMC9858681 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature