Low pretreatment prognostic nutritional index predicts poor survival in breast cancer patients: A meta-analysis.

ABSTRACT:

Background

Prognostic nutritional index (PNI), as an indicator of nutritional immune status, has been shown to be associated with therapeutic effects and survival of solid tumors. However, the prognostic role of PNI before treatment in human breast cancer (BC) is still not conclusive. Hence, we performed this meta-analysis to assess the value of it in prognosis prediction for BC patients.

Materials and methods

We searched PubMed, Embase, Web of Science and EBSCO to identify the studies evaluating the association between PNI and survival such as overall survival (OS), disease-free survival (DFS) of BC, and computed extracted data into hazard ratios (HRs) for OS, DFS and clinicopathological features with STATA 12.0.

Results

A total of 2322 patients with BC from 8 publis

SUBMITTER: Hu G 

PROVIDER: S-EPMC9858712 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature