Recurrence Rates and Pharmacological Treatment for Hemorrhoidal Disease: A Systematic Review.

ABSTRACT:

Introduction

Hemorrhoidal disease (HD) is characterized by prolapse of the inflamed and bleeding vascular tissues of the anal canal. Although HD is associated with a high recurrence rate, there is a lack of understanding around interventions that can reduce recurrence and improve outcomes for patients. As such, a systematic literature review (SLR) was conducted to summarize evidence on epidemiology, recurrence, and efficacy of interventions in HD.

Methods

Real-world evidence (RWE) studies evaluating the incidence, prevalence, or recurrence of HD, as well as SLRs including a meta-analytic component reporting on the efficacy of systemic or topical pharmacological treatments for adults with HD, were included. Systematic searches were conducted in MEDLINE, Embase, Cumulative Ind

SUBMITTER: Lohsiriwat V 

PROVIDER: S-EPMC9859842 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature