T2* quantification using multi-echo gradient echo sequences: a comparative study of different readout gradients.

ABSTRACT: To quantify T2*, multiple echoes are typically acquired with a multi-echo gradient echo sequence using either monopolar or bipolar readout gradients. The use of bipolar readout gradients achieves a shorter echo spacing time, enabling the acquisition of a larger number of echoes in the same scan time. However, despite their relative time efficiency and the potential for more accurate quantification, a comparative investigation of these readout gradients has not yet been addressed. This work aims to compare the performance of monopolar and bipolar readout gradients for T2* quantification. The differences in readout gradients were theoretically investigated with a Cramér-Rao lower bound and validated with computer simulations with respect to the various imaging parameters (e.g., flip angle, T

SUBMITTER: Shin S 

PROVIDER: S-EPMC9860026 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature