Dominance of phage particles carrying antibiotic resistance genes in the viromes of retail food sources.

ABSTRACT: The growth of antibiotic resistance has stimulated interest in understanding the mechanisms by which antibiotic resistance genes (ARG) are mobilized. Among them, studies analyzing the presence of ARGs in the viral fraction of environmental, food and human samples, and reporting bacteriophages as vehicles of ARG transmission, have been the focus of increasing research. However, it has been argued that in these studies the abundance of phages carrying ARGs has been overestimated due to experimental contamination with non-packaged bacterial DNA or other elements such as outer membrane vesicles (OMVs). This study aims to shed light on the extent to which phages, OMVs or contaminating non-packaged DNA contribute as carriers of ARGs in the viromes. The viral fractions of three types of food (chi

SUBMITTER: Blanco-Picazo P 

PROVIDER: S-EPMC9860054 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature