Putative Core Transcription Factors Affecting Virulence in Aspergillus flavus during Infection of Maize.

ABSTRACT: Aspergillus flavus is an opportunistic pathogen responsible for millions of dollars in crop losses annually and negative health impacts on crop consumers globally. A. flavus strains have the potential to produce aflatoxin and other toxic secondary metabolites, which often increase during plant colonization. To mitigate the impacts of this international issue, we employ a range of strategies to directly impact fungal physiology, growth and development, thus requiring knowledge on the underlying molecular mechanisms driving these processes. Here we utilize RNA-sequencing data that are obtained from in situ assays, whereby Zea mays kernels are inoculated with A. flavus strains, to select transcription factors putatively driving virulence-related gene networks. We d

SUBMITTER: Gilbert MK 

PROVIDER: S-EPMC9861280 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature