Ontology highlight
ABSTRACT:
SUBMITTER: Yang F
PROVIDER: S-EPMC9861348 | biostudies-literature | 2023 Jan
REPOSITORIES: biostudies-literature
Yang Feng F Chen Xutao X Zhang Hui H Zhao Guo-Dong GD Yang Huifei H Qiu Jiang J Meng Siyan S Wu Penghan P Tao Liang L Wang Qin Q Huang Gang G
International journal of molecular sciences 20230110 2
BK polyomavirus (BKPyV) infection is the main factor affecting the prognosis of kidney transplant recipients, as no antiviral agent is yet available. A better understanding of the renal-cell-type tropism of BKPyV can serve to develop new treatment strategies. In this study, the single-cell transcriptomic analysis demonstrated that the ranking of BKPyV tropism for the kidney was proximal tubule cells (PT), collecting duct cells (CD), and glomerular endothelial cells (GEC) according to the signatu ...[more]