Effect of Light Emitting Diodes (LED) Exposure on Vitreous Metabolites-Rodent Study.

ABSTRACT: The exposure to blue and white Light emitting diodes (LED) light leads to damage in the visual system with short-term LED light exposure. Chronic exposure, adaptive responses to light, and self-protective mechanisms against LED light exposures need to be explored, and it would be essential to understand the repercussions of LED radiation on vitreous metabolites. A total of 24 male Wistar rats were used in this study, divided into four groups (n = 6 in each group). Three experimental groups of rats were exposed to either blue, white, or yellow LED light for 90 days (12:12 light-dark cycle routine) with uniform illumination (450-500 lux). Standard lab settings were used to maintain control rats. Vitreous fluids were subjected to untargeted metabolomics analysis using liquid chromatogr

SUBMITTER: Theruveethi N 

PROVIDER: S-EPMC9861686 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature