A Disposable Screen Printed Electrodes with Hexagonal Ni(OH)₂ Nanoplates Embedded Chitosan Layer for the Detection of Depression Biomarker.

ABSTRACT: Serotonin (5-hydroxytryptamine (5-HT)) is one of the important neurotransmitters which is released from the endocrine system. An abnormal level of this biomarker leads to several neurological diseases. The accurate assessment of serotonin is the utmost option to start treatment in the early stages of the disease. The current work is focused on the development of a disposable, screen-printed electrochemical sensor for the depression biomarker, serotonin in the physiological pH medium (pH 7.4) with the aid of a hexagonal, Ni(OH)₂-nanoplate (NH-HNP)-embedded chitosan (Chit) and modified, screen-printed carbon electrode (SPCE). Initially, hexagonal nanoplates of Ni(OH)₂ were synthesized by an eco-friendly and simple hydrothermal method. The prepared materials were well ch

SUBMITTER: Moru S 

PROVIDER: S-EPMC9861775 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature