The gastrointestinal microbiome in dairy cattle is constrained by the deterministic driver of the region and the modified effect of diet.

ABSTRACT:

Background

Dairy cattle (Bos taurus), especially Holstein cows, which are the highest-producing dairy animals and are widely bred to provide milk products to humans, rely critically on their associated gastrointestinal tract (GIT) microbiota to digest plant feed. However, the region-specific taxonomic composition and function of the GIT microbiome in dairy cattle and the mechanistic basis for the diet-induced effects remain to be elucidated.  RESULTS: We collected 120 digesta samples from 10 GIT regions of 12 Holstein cows fed forage- and grain-based diets and characterized their GIT microbiome via functional shotgun metagenomics and the resolution of metagenome-assembled genomes. Our results demonstrated that the GIT microbiome was mainly partitioned into three distinct clusters,

SUBMITTER: Lin L 

PROVIDER: S-EPMC9863278 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature