Trapping of a Single Microparticle Using AC Dielectrophoresis Forces in a Microfluidic Chip.

ABSTRACT: Precise trap and manipulation of individual cells is a prerequisite for single-cell analysis, which has a wide range of applications in biology, chemistry, medicine, and materials. Herein, a microfluidic trapping system with a 3D electrode based on AC dielectrophoresis (DEP) technology is proposed, which can achieve the precise trapping and release of specific microparticles. The 3D electrode consists of four rectangular stereoscopic electrodes with an acute angle near the trapping chamber. It is made of Ag-PDMS material, and is the same height as the channel, which ensures the uniform DEP force will be received in the whole channel space, ensuring a better trapping effect can be achieved. The numerical simulation was conducted in terms of electrode height, angle, and channel width. Based

SUBMITTER: Wang Y 

PROVIDER: S-EPMC9863554 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature