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An Imidazo[1,5-a]pyridine Benzopyrylium-Based NIR Fluorescent Probe with Ultra-Large Stokes Shifts for Monitoring SO₂.

ABSTRACT: A mitochondria-targeted NIR probe based on the FRET mechanism was developed. It shows ultra-large Stokes shifts (460 nm) and emission shifts (285 nm). Furthermore, we also realized the imaging of SO₂ in living SKOV-3 cells, zebrafish and living mice which may be useful for understanding the biological roles of SO₂ in mitochondria and in vivo.

SUBMITTER: Cui R

PROVIDER: S-EPMC9863934 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature

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An Imidazo[1,5-a]pyridine Benzopyrylium-Based NIR Fluorescent Probe with Ultra-Large Stokes Shifts for Monitoring SO2.

Cui Renle R Liu Caihong C Zhang Ping P Qin Kun K Ge Yanqing Y

Molecules (Basel, Switzerland) 20230105 2

A mitochondria-targeted NIR probe based on the FRET mechanism was developed. It shows ultra-large Stokes shifts (460 nm) and emission shifts (285 nm). Furthermore, we also realized the imaging of SO2 in living SKOV-3 cells, zebrafish and living mice which may be useful for understanding the biological roles of SO2 in mitochondria and in vivo. ...[more]

PMID: 36677574

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