Multiple S-Layer Proteins of Brevibacillus laterosporus as Virulence Factors against Insects.

ABSTRACT: S-layers are involved in the adaptation of bacteria to the outside environment and in pathogenesis, often representing special virulence factors. Vegetative cells of the entomopathogenic bacterium Brevibacillus laterosporus are characterized by an overproduction of extracellular surface layers that are released in the medium during growth. The purpose of this study was to characterize cell wall proteins of this bacterium and to investigate their involvement in pathogenesis. Electron microscopy observations documented the presence of multiple S-layers, including an outermost (OW) and a middle (MW) layer, in addition to the peptidoglycan layer covering the plasma membrane. After identifying these proteins (OWP and MWP) by mass spectrometry analyses, and determining their gene sequence

SUBMITTER: Ruiu L 

PROVIDER: S-EPMC9864115 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature