Assembly-Induced Emission Enhancement in Glutathione-Capped Bimetallic Gold and Copper Nanoclusters by Al³⁺ Ions and Further Application in Myricetin Determination.

ABSTRACT: A significant emission enhancement (>100-fold) of glutathione-capped bimetallic gold and copper nanoclusters (AuCuNC@GSH) was achieved by assembling with Al³⁺ ions and by assembly-induced emission enhancement (AIEE). Further chelation of myricetin to Al³⁺ resulted in emission quenching of AuCuNC-Al³⁺, which was applied to specifically detect myricetin. Two linear responses were shown in the range of 0-1.5 μM and 1.5-50 μM, separately, leading to a low limit of detection at 8.7 nM. The method was successfully and accurately applied to myricetin determination in grape juice, which showed good application for real samples. Finally, the in-depth mechanism revealed that both the chelation of myricetin and Al³⁺ and the inner filter effect (IFE) between myricetin-Al³⁺ and AuCuNC-Al³⁺ greatly contributed to the quenching response of myricetin. Therefore, the present study provides an easy way to improve the fluorescence property of metal nanoclusters. Additionally, it supplies a cost-effective and easily performed approach to detect myricetin with high selectivity and sensitivity.

SUBMITTER: Bai HJ 

PROVIDER: S-EPMC9864343 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature