Dietary Polyphenols in Relation to Gut Microbiota Composition in Saudi Arabian Females.

ABSTRACT: Polyphenols may modulate gut microbiota; however, limited studies have examined this relationship relative to obesity. We aim to investigate the association between polyphenol intake and gut microbiota composition in relation to obesity indices among Saudi Arabian females. This study included 92 adults stratified by body mass index (BMI) into controls (BMI ≥ 18.5-24.9 kg/m²; n = 48) and cases (BMI ≥ 30.0 kg/m²; n = 44), and further divided into high and low polyphenol intake by median intake (252 mg/1000 kcal/day). Fecal samples were collected to analyze the gut microbiota composition via the whole-genome shotgun sequencing technique. Results showed that Flavonifractor plautii and Clostridium bolteae were positively correlated with polyphen

SUBMITTER: Alsuhaibani MN 

PROVIDER: S-EPMC9864957 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature