Maternal Sepsis in Italy: A Prospective, Population-Based Cohort and Nested Case-Control Study.

ABSTRACT: Maternal sepsis represents a leading cause of mortality and severe morbidity worldwide. In Italy, it is the second cause of direct maternal mortality. Delay in recognition and treatment initiation are the drivers of sepsis-associated adverse outcomes. Between November 2017 and October 2019, the Italian Obstetric Surveillance System coordinated a prospective population-based study on maternal sepsis occurring before or after childbirth from 22 weeks' gestation onward and up to 42 days following the end of pregnancy. A nested 1:2 matched case-control study on postpartum sepsis was also performed. Maternal sepsis was diagnosed for the presence of suspected or confirmed infection alongside signs or symptoms of organ failure. The aim of this study was to assess maternal sepsis incidence and its

SUBMITTER: Ornaghi S 

PROVIDER: S-EPMC9865500 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature