Features of Mycobacterium bovis Complete Genomes Belonging to 5 Different Lineages.

ABSTRACT: Mammalian tuberculosis (TB) is a zoonotic disease mainly due to Mycobacterium bovis (M. bovis). A current challenge for its eradication is understanding its transmission within multi-host systems. Improvements in long-read sequencing technologies have made it possible to obtain complete bacterial genomes that provide a comprehensive view of species-specific genomic features. In the context of TB, new genomic references based on complete genomes genetically close to field strains are also essential to perform precise field molecular epidemiological studies. A total of 10 M. bovis strains representing each genetic lineage identified in France and in other countries were selected for performing complete assembly of their genomes. Pangenome analysis revealed a "closed" pan

SUBMITTER: Charles C 

PROVIDER: S-EPMC9865570 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature