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Visible-Light-Enhanced Antibacterial Activity of Silver and Copper Co-Doped Titania Formed on Titanium via Chemical and Thermal Treatments.

ABSTRACT: Dental implants made of titanium (Ti) are used in dentistry, but peri-implantitis is a serious associated problem. Antibacterial and osteoconductive Ti dental implants may decrease the risk of peri-implantitis. In this study, titania (TiO2) co-doped with silver (Ag) at 2.5 at.% and copper (Cu) at 4.9 at.% was formed on Ti substrates via chemical and thermal treatments. The Ag and Cu co-doped TiO2 formed apatite in a simulated body fluid, which suggests osteoconductivity. It also showed antibacterial activity against Escherichia coli, which was enhanced by visible-light irradiation. This enhancement might be caused by the synergistic effect of the release of Ag and Cu and the generation of •OH from the sample. Dental implants with such a Ag and Cu co-doped TiO2 formed on their surface may reduce the risk of peri-implantitis.

SUBMITTER: Suzuki K 

PROVIDER: S-EPMC9866272 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature

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Visible-Light-Enhanced Antibacterial Activity of Silver and Copper Co-Doped Titania Formed on Titanium via Chemical and Thermal Treatments.

Suzuki Kanae K   Iwatsu Misato M   Mokudai Takayuki T   Furuya Maiko M   Yokota Kotone K   Kanetaka Hiroyasu H   Shimabukuro Masaya M   Yokoi Taishi T   Kawashita Masakazu M  

Molecules (Basel, Switzerland) 20230109 2

Dental implants made of titanium (Ti) are used in dentistry, but peri-implantitis is a serious associated problem. Antibacterial and osteoconductive Ti dental implants may decrease the risk of peri-implantitis. In this study, titania (TiO<sub>2</sub>) co-doped with silver (Ag) at 2.5 at.% and copper (Cu) at 4.9 at.% was formed on Ti substrates via chemical and thermal treatments. The Ag and Cu co-doped TiO<sub>2</sub> formed apatite in a simulated body fluid, which suggests osteoconductivity. It  ...[more]

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