Antiadherent AgBDC Metal-Organic Framework Coating for Escherichia coli Biofilm Inhibition.

ABSTRACT: Surface microbial colonization and its potential biofilm formation are currently a major unsolved problem, causing almost 75% of human infectious diseases. Pathogenic biofilms are capable of surviving high antibiotic doses, resulting in inefficient treatments and, subsequently, raised infection prevalence rates. Antibacterial coatings have become a promising strategy against the biofilm formation in biomedical devices due to their biocidal activity without compromising the bulk material. Here, we propose for the first time a silver-based metal-organic framework (MOF; here denoted AgBDC) showing original antifouling properties able to suppress not only the initial bacterial adhesion, but also the potential surface contamination. Firstly, the AgBDC stability (colloidal, structural and

SUBMITTER: Arenas-Vivo A 

PROVIDER: S-EPMC9866433 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature