Comparison of Safety and Effectiveness of Local or General Anesthesia after Transcatheter Aortic Valve Implantation: A Systematic Review and Meta-Analysis.

ABSTRACT: It remains controversial to choose anesthesia for transcatheter aortic valve implantation (TAVI). A meta-analysis of cohort studies was conducted to assess the efficacy and safety of local anesthesia (LA) compared to general anesthesia (GA) in TAVI. All relevant studies published from 1 January 2002, to 31 June 2022, were searched in Ovid, PubMed, Embase, Web of Science, and Cochrane Library. A total of 34 studies involving 23,480 patients were included in the meta-analysis. TAVI with LA was associated with a significant reduction in hospital stay [WMD = -2.48, 95% CI (-2.80, -2.16), p < 0.00001], operative [WMD = -12.25, 95% CI (-13.73, -10.78), p < 0.00001] and fluoroscopy time [WMD = -3.30, 95% CI (-5.40, -1.19), p = 0.002], and an increased risk of acute kidn

SUBMITTER: Wang L 

PROVIDER: S-EPMC9866516 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature