Quantifying In-Host Quasispecies Evolution.
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ABSTRACT:
SUBMITTER: Gregori J
PROVIDER: S-EPMC9867078 | biostudies-literature | 2023 Jan
REPOSITORIES: biostudies-literature
Publications
Quantifying In-Host Quasispecies Evolution.
Gregori Josep J Ibañez-Lligoña Marta M Quer Josep J
International journal of molecular sciences 20230109 2
What takes decades, centuries or millennia to happen with a natural ecosystem, it takes only days, weeks or months with a replicating viral quasispecies in a host, especially when under treatment. Some methods to quantify the evolution of a quasispecies are introduced and discussed, along with simple simulated examples to help in the interpretation and understanding of the results. The proposed methods treat the molecules in a quasispecies as individuals of competing species in an ecosystem, whe ...[more]
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