Characterization and Genomic Analysis of a Bacteriophage with Potential in Lysing Vibrio alginolyticus.

ABSTRACT: Vibrio alginolyticus is one of the major pathogens causing vibriosis to a variety of aquatic animals as well as bringing about severe food safety concerns. Nowadays, phage therapy has received increasing attention as an alternative to the antibiotics that have being limited for use in aquaculture industries. In this work, a potent bacteriophage, vB_ValM_PVA23 (PVA23), which efficiently infects pathogenic strains of V. alginolyticus, was isolated from sewage water and characterized by microbiological and genomic analyses. Based on the transmission electronic observation, the phage was characterized to be the Myoviridae family. It has a latent period of 10 min and a burst size of 203 PFUs/infected bacterium, and was stable over a broad pH range (5.0-11.

SUBMITTER: Fu J 

PROVIDER: S-EPMC9867112 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature