Attenuation Correction Using Template PET Registration for Brain PET: A Proof-of-Concept Study.

ABSTRACT: NeuroLF is a dedicated brain PET system with an octagonal prism shape housed in a scanner head that can be positioned around a patient's head. Because it does not have MR or CT capabilities, attenuation correction based on an estimation of the attenuation map is a crucial feature. In this article, we demonstrate this method on [¹⁸F]FDG PET brain scans performed with a low-resolution proof of concept prototype of NeuroLF called BPET. We perform an affine registration of a template PET scan to the uncorrected emission image, and then apply the resulting transform to the corresponding template attenuation map. Using a whole-body PET/CT system as reference, we quantitively show that this method yields comparable image quality (0.893 average correlation to reference scan) to using th

SUBMITTER: Jehl M 

PROVIDER: S-EPMC9867435 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature