Non-invasive brain stimulation for fatigue in post-acute sequelae of SARS-CoV-2 (PASC).

ABSTRACT:

Background

and purpose: Fatigue is among the most common persistent symptoms following post-acute sequelae of Sars-COV-2 infection (PASC). The current study investigated the potential therapeutic effects of High-Definition transcranial Direct Current Stimulation (HD-tDCS) associated with rehabilitation program for the management of PASC-related fatigue.

Methods

Seventy patients with PASC-related fatigue were randomized to receive 3 mA or sham HD-tDCS targeting the left primary motor cortex (M1) for 30 min paired with a rehabilitation program. Each patient underwent 10 sessions (2 sessions/week) over five weeks. Fatigue was measured as the primary outcome before and after the intervention using the Modified Fatigue Impact Scale (MFIS). Pain level, anxiety severity and quality

SUBMITTER: Santana K 

PROVIDER: S-EPMC9867562 | biostudies-literature | 2023 Jan-Feb

REPOSITORIES: biostudies-literature