The COVID-19 Vaccines International Pregnancy Exposure Registry (C-VIPER): Protocol and Methodological Considerations.

ABSTRACT:

Introduction

The advent of the coronavirus disease 2019 (COVID-19) pandemic has led to the development of vaccines against severe acute respiratory syndrome coronavirus 2. Prospective evidence regarding safety for pregnant people and their developing fetuses is lacking. The aim of the COVID-19 Vaccines International Pregnancy Exposure Registry (C-VIPER) is to estimate the relative risk of obstetric, neonatal, and infant outcomes by comparing participants vaccinated against COVID-19 during pregnancy to a reference group of people enrolled in the Pregistry International Pregnancy Exposure Registry (PIPER) who remained unvaccinated during pregnancy.

Methods

The C-VIPER and the PIPER are international, non-interventional, real-world cohort studies. Participants receiving a COVID

SUBMITTER: Wyszynski DF 

PROVIDER: S-EPMC9867833 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature