RASopathy mutations open new insights into the mechanism of BRAF activation.

ABSTRACT: Spencer-Smith et al. (2022)¹ investigate multiple functions of the BRAF cysteine-rich domain (CRD), finding distinct classes of RASopathy-associated BRAF mutations and unique features among RAF paralogs that may contribute to the spectrum of mutations observed in disease.

SUBMITTER: Dar AC 

PROVIDER: S-EPMC9867872 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature