Sex difference and intra-operative tidal volume: Insights from the LAS VEGAS study.

ABSTRACT:

Background

One key element of lung-protective ventilation is the use of a low tidal volume (VT). A sex difference in use of low tidal volume ventilation (LTVV) has been described in critically ill ICU patients.

Objectives

The aim of this study was to determine whether a sex difference in use of LTVV also exists in operating room patients, and if present what factors drive this difference.

Design, patients and setting

This is a posthoc analysis of LAS VEGAS, a 1-week worldwide observational study in adults requiring intra-operative ventilation during general anaesthesia for surgery in 146 hospitals in 29 countries.

Main outcome measures

Women and men were compared with respect to use of LTVV, defined as VT of 8 ml kg-1 or less predicted bodyweight (PBW). A VT wa

SUBMITTER: Nijbroek SG 

PROVIDER: S-EPMC9867928 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature