A study on the material properties of novel PEGDA/gelatin hybrid hydrogels polymerized by electron beam irradiation.

ABSTRACT: Gelatin-based hydrogels are highly desirable biomaterials for use in wound dressing, drug delivery, and extracellular matrix components due to their biocompatibility and biodegradability. However, insufficient and uncontrollable mechanical properties and degradation are the major obstacles to their application in medical materials. Herein, we present a simple but efficient strategy for a novel hydrogel by incorporating the synthetic hydrogel monomer polyethylene glycol diacrylate (PEGDA, offering high mechanical stability) into a biological hydrogel compound (gelatin) to provide stable mechanical properties and biocompatibility at the resulting hybrid hydrogel. In the present work, PEGDA/gelatin hybrid hydrogels were prepared by electron irradiation as a reagent-free crosslinking technolog

SUBMITTER: Sener Raman T 

PROVIDER: S-EPMC9868307 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature