First identification of multidrug-resistant Acinetobacter bereziniae isolates harboring bla _NDM-1 from hospitals in South China.

ABSTRACT: This study is a first report on the identification of multidrug-resistant (MDR) Acinetobacter bereziniae among non-baumannii acinetobacters that had previously escaped automated laboratory detection, and characterize their clinical courses of infection at two tertiary-care hospitals in Shenzhen city, China (2015-2017). Herein, definitive identification by PCR was performed with universal and species-specific primers targeting 16S rDNA and rpoB genes, respectively, followed by Sanger sequencing and blast analysis. Antimicrobial susceptibility of A. bereziniae isolates was assessed accordingly. Three of the five identified A. bereziniae isolates exhibited carbapenem-resistance and were subjected to a multiplex PCR assay to detect drug-resistance genes. Sequ

SUBMITTER: Mo XM 

PROVIDER: S-EPMC9868374 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature