Altered brain connectivity in hyperkinetic movement disorders: A review of resting-state fMRI.

ABSTRACT:

Background

Hyperkinetic movement disorders (HMD) manifest as abnormal and uncontrollable movements. Despite reported involvement of several neural circuits, exact connectivity profiles remain elusive.

Objectives

Providing a comprehensive literature review of resting-state brain connectivity alterations using resting-state fMRI (rs-fMRI). We additionally discuss alterations from the perspective of brain networks, as well as correlations between connectivity and clinical measures.

Methods

A systematic review was performed according to PRISMA guidelines and searching PubMed until October 2022. Rs-fMRI studies addressing ataxia, chorea, dystonia, myoclonus, tics, tremor, and functional movement disorders (FMD) were included. The standardized mean difference was used to su

SUBMITTER: Marapin RS 

PROVIDER: S-EPMC9868884 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature