Use of inhaled ipratropium bromide to improve exercise-induced laryngeal obstruction cannot be recommended.

ABSTRACT:

Introduction

Exercise-induced laryngeal obstruction (EILO) is a common cause of exertional breathing problems in young adults. Current management generally consists of breathing advice, speech therapy, inspiratory muscle training or supraglottoplasty in highly motivated subjects with supraglottic collapse. Inhaled ipratropium bromide (IB) is a muscarinic receptor antagonist used to treat asthma that is suggested in a few reports to improve EILO symptoms. The aim of the present study was to investigate effects of inhaled IB in EILO diagnosed by continuous laryngoscopy exercise (CLE) test and classified by CLE scores.

Methods

A randomised crossover trial was conducted at Haukeland University Hospital, Bergen, Norway, enrolling participants diagnosed with EILO defined by charac

SUBMITTER: Muralitharan P 

PROVIDER: S-EPMC9868967 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature