Lymphoepithelial carcinoma of the head and neck: a SEER analysis of prognostic factors for survival.

ABSTRACT:

Objective

To explore the epidemiological characteristics of patients with lymphoepithelial carcinoma (LEC) of the head and neck and the prognostic factors.

Methods

We conducted a retrospective cohort study of cases of head and neck LEC retrieved from the Surveillance, Epidemiology and End Results database. Kaplan-Meier survival analysis and the log-rank test were employed to assess overall survival (OS) and cancer-specific survival (CSS). Univariate and multivariate analyses were used to construct Cox regression models. We established nomograms to predict OS and CSS among patients with nasopharyngeal LEC, who were divided into high- and low-risk groups based on the OS nomograms to compare the effects of treatment using the restricted mean survival time (RMST).

Results

SUBMITTER: Wei J 

PROVIDER: S-EPMC9869209 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature