Metals and risk of incident metabolic syndrome in a prospective cohort of midlife women in the United States.

ABSTRACT: Exposure to metals may contribute to the development of metabolic syndrome (MetS); however, evidence from midlife women who are at greater risk of cardiometabolic disease is limited. We assessed the associations of 15 urinary metal concentrations with incident MetS in a prospective cohort of midlife women in the United States. The study population included 947 White, Black, Chinese and Japanese women, aged 45-56 years, free of MetS at baseline (1999-2000), who participated in the Study of Women's Health Across the Nation Multi-Pollutant Study. Fifteen metals were detected in almost all participants urine samples using inductively coupled plasma mass spectrometry at the baseline. Incident MetS was identified annually through 2017 as having at least three of the following five components: hi

SUBMITTER: Wang X 

PROVIDER: S-EPMC9869389 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature