Bacterial meningitis in adults: a retrospective study among 148 patients in an 8-year period in a university hospital, Finland.

ABSTRACT:

Background

Bacterial meningitis (BM) causes significant morbidity and mortality. We investigated predisposing factors, clinical characteristics, spectrum of etiological bacteria, and clinical outcome of community-acquired and nosocomial BM.

Methods

In this retrospective study we analyzed data of 148 adults (age > 16 years) with BM treated in Turku University Hospital, Southwestern Finland, from 2011 to 2018. Besides culture- or polymerase chain reaction (PCR)-positive cases we also included culture-negative cases with laboratory parameters strongly suggestive of BM and those with meningitis-related findings in imaging. We used Glasgow Outcome Scale (GOS) score 1-4 to determine unfavorable outcome.

Results

The median age of patients was 57 years and 48.6% were male. Ce

SUBMITTER: Niemela S 

PROVIDER: S-EPMC9869503 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature