Biodegradable smart materials with self-healing and shape memory function for wound healing.

ABSTRACT: Notwithstanding the rapid development of suture elastomers to meet the needs of practical surgery, utilizing the elastomers' self-healing function as a surgical suture to facilitate the healing of wounds has not been addressed. Here, a biodegradable aliphatic polycarbonate smart elastomer, mPEG₁₁₃-b-PMBC _n , was synthesized from aliphatic polycarbonate monomer with methoxy polyethylene glycol (mPEG₁₁₃, 5.0 kDa) as initiator, which exhibited excellent mechanical properties, highly efficient self-repairing, and remarkable shape memory behavior. The polymers possess outstanding self-healing ability for 150 min. Meanwhile, after 46.33 ± 1.18 s, the temporary shape of the obtained polymer had been recovered. The results of biocompatibility tests re

SUBMITTER: Sun S 

PROVIDER: S-EPMC9869863 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature