Differential response of positive valence systems to psychotherapy for late-life depression: A pilot study.

ABSTRACT:

Background

Depression is characterized by deficits in the positive valence systems (PVS), which also decline with age. However, few studies have examined changes in PVS as a mechanism of treatment for depression, and none have done so using reward-focused interventions in older adults.

Aim

The aim of this proof-of-concept study was to investigate changes in two event-related potential measures of PVS function, the late positive potential and the reward positivity, during psychotherapy designed to treat late-life depression by increasing rewarding experiences.

Methods

Eighteen adults age ≥ 60 with major depressive disorder recruited for a larger randomized controlled trial received 9 weeks of Problem-Solving Therapy or Engage therapy. The late positive potential and th

SUBMITTER: Bress JN 

PROVIDER: S-EPMC9870625 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature