Poverty from fetal life onward and child brain morphology.

ABSTRACT: Poverty is a risk factor for impaired child development, an association possibly mediated by brain morphology. Previous studies lacked prospective poverty assessments during pregnancy and did not stratify by majority/minority status. We investigated the association of household poverty from fetal life forward with brain morphological differences at age 10 years, in 2166 mother-child dyads. Overall, the results showed no associations between any poverty exposure early in life and brain volumes. However, there was the evidence of timing effects: children exposed to poverty in utero had smaller amygdala volumes (B =  - 0.18, 95%CI - 0.30; - 0.07, p_FDR-adjusted = 0.009). There were also differences in associations by majority/minority status (cerebral white matter: p for interaction

SUBMITTER: Koyama Y 

PROVIDER: S-EPMC9870876 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature