Comparison of ultrasonography and pathology features between children and adolescents with papillary thyroid carcinoma.

ABSTRACT:

Objective

To compare the ultrasonography and pathology features between children and adolescents with papillary thyroid carcinoma (PTC).

Methods

A total of 53 patients who were surgically diagnosed with childhood or adolescent PTC between 2017 and 2022 were included in this study. The pre-operative ultrasonography, post-operative histology, and molecular and clinical characteristics were retrospectively analyzed.

Results

No differences were observed in composition, echogenicity, and shape using ultrasonography. Moreover, there was a significantly higher rate of extrathyroidal extension, punctate echogenic foci, and lymph node metastases in children compared to adolescents. The molecular analysis showed that BRAF^V600E mutations are the most prevalent abnorma

SUBMITTER: Jie Y 

PROVIDER: S-EPMC9871215 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature