The submandibular and sublingual glands maintain oral microbial homeostasis through multiple antimicrobial proteins.

ABSTRACT:

Introduction

Oral microbial homeostasis is a key factor affecting oral health, and saliva plays a significant role in maintaining oral microbial homeostasis. The submandibular gland (SMG) and sublingual gland (SLG) together produce the most saliva at rest. Organic ingredients, including antimicrobial proteins, are rich and distinctive and depend on the type of acinar cells in the SMG and SLG. However, the functions of the SMG and SLG in maintaining oral microbial homeostasis have been difficult to identify and distinguish, given their unique anatomical structures.

Methods

In this study, we independently removed either the SMG or SLG from mouse models. SMGs were aseptically removed in three mice in the SMG-removal group, and SLGs were aseptically removed in three mice in the

SUBMITTER: Li Y 

PROVIDER: S-EPMC9872150 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature