Effects of antipsychotic and anticholinergic medications on cognition in chronic patients with schizophrenia.

ABSTRACT:

Background

Patients with psychosis frequently use a variety of psychotropic medicines, many of which have anticholinergic effects that can impair cognition. Therefore, this study aimed to evaluate whether there is an association between medications used for neuropsychological disorders/symptoms and cognition in patients with schizophrenia, focusing on their anticholinergic load and antipsychotic doses.

Study design

A cross-sectional study between July 2019 and Mars 2020 at the Psychiatric Hospital of the Cross-Lebanon enrolled 120 inpatients diagnosed with schizophrenia. The total anticholinergic burden was calculated based on the Anticholinergic Drug Scale (ADS), and the chlorpromazine equivalent dose was calculated using the Andreasen method to assess the relative antipsyc

SUBMITTER: Haddad C 

PROVIDER: S-EPMC9872384 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature