Faecal haemoglobin concentrations are associated with all-cause mortality and cause of death in colorectal cancer screening.

ABSTRACT:

Background

Colorectal cancer (CRC) screening reduces all-cause and CRC-related mortality. New research demonstrates that the faecal haemoglobin concentration (f-Hb) may indicate the presence of other serious diseases not related to CRC. We investigated the association between f-Hb, measured by a faecal immunochemical test (FIT), and both all-cause mortality and cause of death in a population-wide cohort of screening participants.

Methods

Between 2014 and 2018, 1,262,165 participants submitted a FIT for the Danish CRC screening programme. We followed these participants, using the Danish CRC Screening Database and several other national registers on health and population, until December 31, 2018. We stratified participants by f-Hb and compared them using a Cox proportional haz

SUBMITTER: Kaalby L 

PROVIDER: S-EPMC9872406 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature