Predictors of adverse diastolic remodeling in non-diabetic patients presenting with ST-elevation myocardial infarction.

ABSTRACT:

Background

Adverse systolic remodeling after ST-elevation myocardial infarction (STEMI) is associated with poor clinical outcomes. However, little is known about diastolic remodeling. The purpose of this study was to identify the factors leading to diastolic remodeling.

Methods

Echocardiography was performed during hospitalization and at 4 months follow-up in 267 non-diabetic STEMI patients from the GIPS-III trial. As parameters of diastolic remodeling we used (1.) the E/e' at 4 months adjusted for the E/e' at hospitalization and (2.) the change in E/e' between hospitalization and 4 months. Multivariable regression models correcting for age and sex were constructed to identify possible association of clinical and angiographic variables as well as biomarkers with diastolic re

SUBMITTER: Al Ali L 

PROVIDER: S-EPMC9872414 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature