Effects of antenatal corticosteroids on neonatal outcomes in twin and singleton pregnancies: a Korean national cohort study.

ABSTRACT:

Objective

To investigate whether effects of antenatal corticosteroids on neonatal outcomes in preterm infants with very low birth weight were different by plurality.

Design

Nationwide prospective cohort study.

Patients

Twins and singletons with very low birth weight (<1500 g) who were born between 23⁺⁰ and 33⁺⁶ weeks of gestation and registered in the Korean Neonatal Network from January 2014 to December 2019.

Main outcome measures

Morbidity and mortality before discharge from neonatal intensive care unit.

Results

Among a total of 9531 preterm infants with very low birth weight, there were 2364 (24.8%) twins and 7167 (75.2%) singletons. While 83.9% of singletons were exposed to at least one dose of antenatal corticosteroids, so were

SUBMITTER: Bae SP 

PROVIDER: S-EPMC9872481 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature