A specific tongue microbiota signature is found in patients displaying an improvement of orosensory lipid perception after a sleeve gastrectomy.

ABSTRACT:

Introduction

A preferential consumption of low-fat foods is reported by most of the patients after a vertical sleeve gastrectomy (VSG). The fact that a recent study shed light on a relationship between oral microbiota and fat taste sensitivity in obese patients prompted us to explore whether such a connection also exists in the context of a VSG.

Methods

Thirty-two adult female patients with a severe obesity (BMI = 43.1 ± 0.7 kg/m²) and candidates for a VSG were selected. Oral microbiota composition surrounding the gustatory circumvallate papillae (CVP) and the lipid perception thresholds were explored before and 6 months after surgery.

Results

VSG was found to be associated both with a qualitative (compositional changes) and quantitative (lower gene richnes

SUBMITTER: Bernard A 

PROVIDER: S-EPMC9874242 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature