Microencapsulated phage composites with increased gastrointestinal stability for the oral treatment of Salmonella colonization in chicken.

ABSTRACT: Salmonella infection, one of the common epidemics in the livestock and poultry breeding industry, causes great economic losses worldwide. At present, antibiotics are the most commonly used treatment for Salmonella infection, but the widespread use of antibiotics has increased drug resistance to Salmonella. Phage therapy has gradually become an alternative method to control Salmonella infection. However, phage, a specific virus that can infect bacteria, has poor stability and is prone to inactivation during treatment. Microencapsulated phage microspheres can effectively solve this problem. Accordingly, in this study, Salmonella phages were microencapsulated, using the xanthan gum/sodium alginate/CaCl₂/chitooligosaccharides method, to improve the

SUBMITTER: Zhang B 

PROVIDER: S-EPMC9875011 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature