Biosynthesis of aliphatic plastic monomers with amino residues in Yarrowia lipolytica.

ABSTRACT: Introduciton: The α,ω-diamines (NH₂-(CH₂)_n-NH₂) and ω -amino fatty acids (NH₂-(CH₂)_n-COOH) have been widely used as building blocks in polymerindustries. Medium- to long-chain (C₈ to C₁₈) fatty acid monomers with amino residues are almost exclusively produced via chemical processes that generate hazardous waste and induce severe environmental problems, such as global warming and pollution. Here, we present the construction platformstrains of Yarrowia lipolytica a cheese-ripening yeast, for direct biotransformation of hydrocarbons into medium- to long-chain α,ω-diamines and ωamino fatty acids using metabolic engineering of endogenous fatty acid ω- and β-oxidation pathways

SUBMITTER: Park G 

PROVIDER: S-EPMC9875067 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature