Dataset Information

Hypnosis on patients treated with adjuvant chemotherapy for breast cancer: A feasibility study.

ABSTRACT:

Background

Acceptability and tolerance of chemotherapy on patients treated for breast cancer remain challenging. Complementary approaches such as hypnosis may have a favorable impact both at the time of announcing and during chemotherapy, due to the notorious anxiety, distress, and self-perceived dysfunction. The objective of the study was that the patients complied with at least four self-hypnosis sessions out of the six cycles of chemotherapy.

Methods

This open, prospective longitudinal study assessed feasibility of compliance to self-hypnosis during chemotherapy in an outpatients setting. Training sessions were given by a hypnotherapist. Throughout each cycle of chemotherapy, the patient had to use self-hypnosis to better control her anxiety or any difficulties. Nurses could offer help to the patient. Chemotherapy-associated side effects were evaluated through the NCI-Common Toxicity Criteria for Adverse Events v 4.03; moreover, side effects as pain, nausea, vomiting, fatigue, and anxiety were also evaluated during chemotherapy using a visual analogic scale. Health-related quality of life, emotional distress (anxiety and depression), and cancer-related fatigue were assessed (at inclusion, end of chemotherapy and 3 months later) using the EORTC QLQ-C30 and QLQ-BR23, HADS and MFI-20 questionnaires, respectively. The number of patients screened and actually included in the study was reported, as the reasons for refusal.

Results

Thirty-five patients were included with a median age of 55 years (35-78). All patients received a hypnosis training session. The overall compliance with self-hypnosis was 68.6% (95% CI: 50.7%-83.2%), meaning that more than two thirds of patients performed at least four sessions of self-hypnosis. According to NCI-CTCAE, Grade 2 nausea and vomiting was observed in 45.7% and 22.9%, respectively, Grade 2 fatigue in 62.9%. Based on the HADS questionnaire, anxiety increased at the end of the chemotherapy and returned to the initial value 3 months later (p = .97) whereas depression significantly decrease 3 months after the end of chemotherapy with respect to the inclusion (p = .003). Role, emotional, and cognitive functioning were slightly affected throughout the treatment, in contrast to dyspnea or physical functioning.

Conclusion

Our study showed that self-hypnosis was feasible on patients newly diagnosed for breast cancer receiving chemotherapy.

SUBMITTER: Fabbro M

PROVIDER: S-EPMC9875600 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature

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Hypnosis on patients treated with adjuvant chemotherapy for breast cancer: A feasibility study.

Fabbro Michel M Jacot William W Jarlier Marta M Guiu Séverine S D'Hondt Véronique V Pouderoux Stéphane S Champoiral Patrice P Janiszewski Chloé C Nicklès Isabelle I

Cancer reports (Hoboken, N.J.) 20221027 1

<h4>Background</h4>Acceptability and tolerance of chemotherapy on patients treated for breast cancer remain challenging. Complementary approaches such as hypnosis may have a favorable impact both at the time of announcing and during chemotherapy, due to the notorious anxiety, distress, and self-perceived dysfunction. The objective of the study was that the patients complied with at least four self-hypnosis sessions out of the six cycles of chemotherapy.<h4>Methods</h4>This open, prospective long ...[more]

PMID: 36302744

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Dataset Information

Hypnosis on patients treated with adjuvant chemotherapy for breast cancer: A feasibility study.

Background

Methods

Results

Conclusion

Publications

Hypnosis on patients treated with adjuvant chemotherapy for breast cancer: A feasibility study.

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