Effect of COVID-19 vaccination on the SARS-CoV-2 transmission among social and household close contacts: A cohort study.

ABSTRACT:

Background

COVID-19 vaccination was expected to reduce SARS-CoV-2 transmission, but the relevance of this effect remains unclear. We aimed to estimate the effectiveness of COVID-19 vaccination of the index cases and their close contacts in reducing the probability of SARS-CoV-2 transmission.

Methods

Transmission of SARS-CoV-2 infection was evaluated in two cohorts of adult close contacts of COVID-19 confirmed cases (social and household settings) by COVID-19 vaccination status of the index case and the close contact, from April to November 2021 in Navarre, Spain. The effects of vaccination of the index case and the close contact were estimated as (1-adjusted relative risk) × 100%.

Results

Among 19,631 social contacts, 3257 (17%) were confirmed with SARS-CoV-2. COVID-1

SUBMITTER: Martinez-Baz I 

PROVIDER: S-EPMC9876028 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature