The impact of bariatric surgery on macronutrient malabsorption depends on the type of procedure.

ABSTRACT:

Introduction

Bariatric surgery, currently the most effective treatment for morbidly obese patients, may induce macronutrient malabsorption depending on the type of procedure. Macronutrient malabsorption affects the supply of substrates to the colon, subsequent microbial fermentation and possibly colonic health.

Methods

Using isotope technology, we quantified the extent of macronutrient and bile acid malabsorption and its impact on colonic protein fermentation in patients after Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) and in controls. Participants consumed a single test meal (day 0) that contained intrinsically labeled (¹³C, ¹⁵N, and ²H) egg protein for quantification of protein digestion, malabsorption and fermentation, res

SUBMITTER: Evenepoel C 

PROVIDER: S-EPMC9877414 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature